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Test Code 274 Parathyroid Hormone (PTH), Intact with Minerals

Important Note

Human Anti-Mouse Antibodies (HAMA) may be present in samples from patients who have received immunotherapy utilizing monoclonal antibodies. Additionally, other heterophile antibodies such as human anti-goat antibodies may be present in patient samples. Manufacturers formulate assays to minimize the effects of these antibodies; however careful evaluation of patient results must be done when patients are known to have such antibodies.

Additional Codes

ALAB: PTHMIN

PowerChart: PTH Intact with Minerals

 

Specimen Requirement

0.5 mL serum or plasma is required.

Additional Specimen Collection Information

Collect blood in a lithium heparin, green-top, red-top. PST and SST (gel tubes) are acceptable.Serum or plasma should be separated from contact with the cells within 2 hours of collection. Specimens not centrifuged within 4 hours of collection may be rejected. Refrigerate the specimen if unable to assay within 8 hours of collection. Samples with ≥3+ lipemia must be cleared prior to analysis.

Useful For

Diagnosis and differential diagnosis of hypercalcemia

Diagnosis of primary, secondary, and tertiary hyperparathyroidism

Diagnosis of hypoparathyroidism

Monitoring end-stage renal failure patients for possible renal osteodystrophy

Performance

Testing is performed Monday through Sunday.

Typically completed the same day the specimen arrives at the testing site.

CPT Code Information

83970: Chemistry: Parathormone (parathyroid hormone)

82310: Chemistry: Calcium, total

84100: Chemistry: Phosphorus inorganic (phosphate)

82565: Chemistry: Creatinine; blood

LOINC Code Information

2731-8 Parathyrin.Intact [Mass/Volume] In Serum Or Plasma

Test Method

PTH: Two-Site Immunoenzymatic ("Sandwich") Assay; Beckman

Calcium: Ion Specific Electrode; Beckman

Phosphorus: Timed Endpoint Method; Beckman

Creatinine: Jaffe Rate; Beckman

GFR: Calculated

Reference Values

PTH: 15-65 pg/mL

Calcium: 8.5-10.5 mg/dL

  • Critical Values:
    • Low: < 6.0 mg/dL
    • High: > 13.0 mg/dL

Phosphorus: 2.0-4.5 mg/dL

Creatinine: 0.5-1.5 mg/dL

GFR: ≥ 60 mL/min/1.73m2