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Test Code 416 Hepatitis B Surface Antibody, Qualitative and Quantitative

Important Note

This assay does not differentiate between vaccine-induced immune response and HBV infection.

Additional Codes

ALAB: HEPBAB

PowerChart: Hepatitis B Surface Antibody QL/QN

MA Cerner: Hepatitis B Surface Antibody

Test Method

Two-Step Immunoassay; Abbott Architect

Specimen Requirement

1.0 mL serum or plasma is required.

Additional Specimen Collection Information

Collect blood in a lithium heparin, green-top, EDTA purple-top or red-top tube. PST and SST (gel tubes) are acceptable. Serum or plasma should be separated from contact with the cells within 2 hours of collection. Specimens not centrifuged within 4 hours of collection may be rejected. Refrigerate the specimen if unable to assay within 8 hours of collection. Samples with >1+ lipemia must be cleared prior to analysis.

Performance

Testing is performed Monday through Sunday.

Routine: Typically completed within 4 hours after the specimen arrives at the testing site.

STAT: Typically completed within 2 hours after the specimen arrives at the testing site.

Reference Values

Qualitatiive: Reportes as Nonreactive, Equivocal or Reactive

Quantitative:

  • Reactive: (>12.0 mIU/mL) Indicates acquired immunity from HBV vaccination or recovery from acute or chronic Hepatitis B Virus (HBV) infection.
  • Equivocal: (8.0-12.0 mIU/mL) The immune status should be further assessed.
  • Nonreactive: (<8.0 mIU/mL) Indicates inadequate immune response to HBV vaccination or a lack of recovery from acute or chronic Hepatitis B Virus infection. 

CPT Code Information

86706 Testing for Infectious Disease Antibodies, Hepatitis B surface, antibody

 

United Healthcare requires a signed ABN.

Useful For

Identifying previous exposure to Hepatitis B Virus

Determining adequate immunity from Hepatitis B vaccination

 

LOINC Code Information

22322-2 Hepatitis B Virus Surface Ab [Presence] In Serum

16935-9 Hepatitis B virus Surface Ab [Units/Volume] In Serum