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Test Code 786 Lipid Cascade (Reflexes to LDL, Direct)

Important Note

When the Triglyceride results are >400 mg/dL authorization has been obtained to reflex to order, run and report an LDL, Direct.

Current lipid guidelines are based on fasting samples. While there are likely only minor changes between fasting and non-fasting parameters, cardiovascular risk assessment using non-fasting samples are not yet well established.

Additional Codes

ALAB: LIPC

PowerChart: Lipid Cascade

MA Cerner: Lipid Panel

Specimen Requirement

0.5 mL serum or plasma is required.

Additional Specimen Collection Information

Collect blood in a lithium heparin, green-top or red-top tube. PST and SST (gel tubes) are acceptable. A 12 hour fast prior to collection is preferred but not required. Refrigerate the specimen if unable to assay within 8 hours of collection. It is recommended that the serum or plasma be separated from contact with cells within 2 hours from time of collection. Specimens not centrifuged within 4 hours of collection may be rejected. If the patient is unable to be redrawn, the test may be performed at the request of the ordering clinician and results will carry a disclaimer. (Disclaimer: the specimen was not received in the recommended fashion (delayed cell separation from serum or plasma. Results should be interpreted with caution.)

Useful For

Cardiovascular risk assessment

Performance

Testing is performed Monday through Sunday.

Typically completed the same day order is received.

CPT Code Information

80061 Multi-Test Laboratory Panels: Lipid Panel

LOINC Code Information

57698-3 Lipid Panel With Direct LDL-Serum or Plasma

Test Method

MercyOne: 

Cholesterol: Timed Endpoint Method; Beckman DXC880i
HDL: Liquid N-Geneous HDL Method; Beckman DXC880i
Triglyceride: Timed Endpoint Method; Beckman DXC880i

MA:

Cholesterol: Enzymatic Colorimetric Method; Roche Cobas 6000
HDL: Enzymatic Colorimetric Method; Roche Cobas 6000
Triglyceride: Enzymatic Colorimetric Method; Roche Cobas 6000

Reference Values

Cholesterol:

  • Adult: < 200 mg/dL
  • Pediatric (2-17 years): < 170 mg/dL

Triglyceride:

  • Adult: < 150 mg/dL
  • Pediatric
    • 2-9 years:  < 75 mg/dL
    • 10-17 years: < 90 mg/dL

HDL:

  • Adult: ≥ 40 mg/dL
  • Pediatric (2-17 years): > 45 mg/dL

LDL:

  • Adult: < 100 mg/dL (calculated)
  • Pediatric (2-17 years): < 110 mg/dL (calculated)

Non-HDL Cholesterol:

  • Adult: < 130 mg/dL (calculated)
  • Pediatric (2-17 years): < 120 mg/dL (calculated)