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Test Code CMVGM Cytomegalovirus (CMV) Antibodies, IgM and IgG, Serum

Important Note

The performance of this test has not been established for use in a pediatric population, neonates and immunocompromised patients.

Additional Codes

ALAB: CMVGM

Powerchart: Cytomegalovirus (CMV) IgG IgM Antibodies

MA Cerner: Cytomegalovirus Ab, G&M

Specimen Requirement

Serum is preferred, EDTA or heparinized plasma are also acceptable. Gel tubes are acceptable.

Additional Specimen Collection Information

Collect blood in a serum or plasma gel tube (EDTA or heparin).

  • Minimum volume: 500 mcL
  • Hemolysis: > 2+ not acceptable
  • Lipemia: > 3+ must be ultracentrifuged
  • Icterus: no significant interference noted
  • Storage: specimen is stable for up to 7 days refrigerated; freeze at -20oC for long term storage.
    Thoroughly mix thawed specimens; it is also recommended to centrifuge thawed specimens to remove gross particulate matter. Avoid multiple freeze-thaw cycles (up to 3 cycles are acceptable).

Test Method

Multiplex Flow Immunoassay; BioRad BioPlex

Performance

Testing is performed Monday through Sunday.
Routine: Typically completed within 4 hours after the specimen arrives at the testing site.

Reference Value

CMV IgM: Negative
CMV IgG: Negative

CPT Code Information

86644 Antibody; Cytomegalovirus (CMV)
86645 Antibody; Cytomegalovirus (CMV), IgM

Useful For

  • Diagnosis of primary, acute phase infection with cytomegalovirus (CMV), especially in patients with infectious mononucleosis and pregnant women who, based on clinical signs or exposure, may have primary CMV infection
  • Determining whether a patient (especially transplant recipients, organ and blood donors) has had a recent infection or previous exposure to CMV

LOINC Code Information

13949-3 Cytomegalovirus IgG Ab [Presence] in Serum by Immunoassay
24119-0 Cytomegalovirus IgM Ab [Presence] in Serum by Immunoassay