Test Code H08 NTD Screen: AFP Only
Additional Codes
ALAB: AFPSHL
PowerChart: NTD Screen: AFP Only
MA Cerner: Maternal Screen NTD
Test Method
Quantitative Chemiluminescent Immunoassay
Specimen Requirement
1 mL of serum is required. The specimen is collected during the second trimester between 15 weeks to 20 weeks 6 days.
Additional Specimen Collection Information
- Collect blood in a plain, red-top tube(s) or serum gel tube(s).
- Allow the blood to clot, then centrifuge and remove serum (at least 1 mL) from the tube and transfer to a tube labeled with patient name or unique identifier, age or date of birth and the date of collection. UNLABELED SPECIMENS WILL NOT BE TESTED.
- Keep the serum refrigerated, but DO NOT FREEZE, if not sending immediately.
- Wrap the tube in absorbent material and place in a biohazard bag.
- Roll the specimen in the bag and place in a SHL mailer with an “A”-code self-adhesive wrapper provided.
- Ship at ambient temperature.
- Send with the completed Iowa Maternal Screen Test Request
form.
SHL-Maternal Screen Request Form- Fill out the form as completely as possible.
- Missing information may delay screening results.
- Incorrect information, especially incorrect dating will result in inaccurate risk management.
- Be sure to include the clinician name and phone number and the sonographer's name.
- The specimen must be received by SHL within 9 days of collection date.
Performance
Test performed Monday through Sunday
Reference Value
Negative
Detection rate: 85% neural tube defects
For test interpretation or revised dating information contact UIHC OB/GYN Counseling Office: (319)356-3561.
CPT Code Information
82105 Chemistry: Alpha-fetoprotein (AFP); serum
Useful For
Detection of open neural tube defects.
LOINC Code Information
In process