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Test Code HSVG Herpes Simplex Virus (HSV) Types 1 and 2 AB, IgG

Important Note

The performance of this test has not been established for use in a pediatric population, neonates and immunocompromised patients.

Additional Codes

ALAB: HSVG

Powerchart: Herpes Simplex I and II IgG Antibodies

MA Cerner: Herpes Simplex Virus (HSV) Types 1 and 2 Ab, IgG

Specimen Requirement

Serum or Plasma (EDTA or Heparin) is required; gel tubes a preferred

Additional Specimen Collection Information

Collect blood in a serum or plasma gel tube (EDTA or heparin). Red-top serum, EDTA lavender-top or Heparin green-top are also acceptable.

  • Minimum volume: 500 mcL
  • Hemolysis: > 2+ not acceptable
  • Lipemia: > 3+ must be ultracentrifuged
  • Icterus: no significant interference
  • Storage: specimen is stable for up to 7 days refrigerated; freeze at -20oC for long term storage.
    Thoroughly mix thawed specimens; it is also recommended to centrifuge thawed specimens to remove gross particulate matter. Avoid multiple freeze-thaw cycles (up to 3 cycles are acceptable).

Test Method

Multiplex Flow Immunoassay; BioRad BioPlex

Performance

Testing is performed Monday through Sunday.
Routine: Typically completed within 4 hours after the specimen arrives at the testing site.

CPT Code Information

86695   Qualitative or semi-qualitative immunoassays performed by multiple-step methods for detection of Herpes simplex type 1
86696   Qualitative or semi-qualitative immunoassays performed by multiple-step methods for detection of Herpes simplex type 2

Useful For

  • As an aid for the presumptive diagnosis of HSV-1 or HSV-2 infection
  • Detection and differentiation of antibodies to herpes subtype 1 and  2

LOINC Code Information

 27948-9  Herpes simplex virus 1+2 IgG Ab [Units/volume] in Serum by Immunoassay

Reference Value

Negative