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Test Code OXYCU Oxycodone with Metabolite Confirmation, Random, Urine

Additional Codes


Powerchart: Oxycodone with Metabolite Confirmation Urine


Useful For

Detection and quantification of oxycodone, oxymorphone, noroxycodone, and noroxymorphone in urine

Reporting Name

Oxycodone w/metabolite Conf, U

Specimen Type


Ordering Guidance

For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody testing, order OXYCX / Oxycodone with Metabolite Confirmation, Chain of Custody, Random, Urine.


Additional drug panels and specific requests are available; call 800-533-1710 or 507-266-5700.

Additional Testing Requirements

If urine creatinine is required or adulteration of the sample is suspected, the following test should also be ordered, ADULT / Adulterants Survey, Random, Urine.

Specimen Required

Supplies: Sarstedt 5 mL Aliquot Tube (T914)

Collection Container/Tube: Plastic urine container

Submission Container/Tube: Plastic, 5-mL tube

Specimen Volume: 3 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.

Additional Information:

1. No specimen substitutions.

2. STAT requests are not accepted for this test.

3. Submitting <1 mL will compromise our ability to perform all necessary testing.

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  14 days

Reject Due To

Gross hemolysis OK
Gross icterus OK

Reference Values


Cutoff concentrations by liquid chromatography-tandem mass spectroscopy:

Oxycodone: 25 ng/mL

Noroxycodone: 25 ng/mL

Oxymorphone: 25 ng/mL

Noroxymorphone: 25 ng/mL

Day(s) Performed

Monday through Friday

Report Available

2 to 5 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information


G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
OXYCU Oxycodone w/metabolite Conf, U 94304-3


Result ID Test Result Name Result LOINC Value
62616 Oxycodone-by LC-MS/MS 16249-5
42010 Noroxycodone-by LC-MS/MS 61425-5
35965 Oxymorphone-by LC-MS/MS 17395-5
42011 Noroxymorphone-by LC-MS/MS 90894-7
36022 Oxycodone Interpretation 19643-6

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Secondary ID



If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.