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HelpTest Code PN23M Streptococcus pneumoniae IgG Antibodies, 23 Serotypes, Serum
Additional Codes
ALAB: YPN23
Powerchart: NA
Ordering Guidance
This test is the preferred test for patients previously tested for Streptococcus pneumoniae serotypes (as part of follow up testing or part of pre/post vaccine assessment).
The preferred test for patients being evaluated for possible immunodeficiency or for assessment of pneumococcal vaccination response (initial evaluation) is PNTOR / Streptococcus pneumoniae IgG Antibodies, Total, with Reflex, Serum
The preferred test for patients previously tested for total Streptococcus pneumoniae antibodies (as part of follow up testing or part of pre/post vaccine assessment) is PNTO / Streptococcus pneumoniae IgG Antibodies, Total, Serum
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into plastic vial
Secondary ID
619921Useful For
Assessing the IgG antibody response to active immunization with nonconjugated, 23-valent pneumococcal vaccines
Assessing the IgG antibody response to active immunization with conjugated 13-valent, 15-valent and 20-valent pneumococcal vaccines
Determining the ability of an individual to produce an antibody response to polysaccharide antigens, as part of the evaluation for humoral or combined immunodeficiencies
Method Name
Bead-Based Multiplex Immunoassay
Reporting Name
S. pneumoniae IgG Ab,23 serotypes,SSpecimen Type
SerumSpecimen Minimum Volume
0.4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 21 days |
| Frozen | 21 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
Results are reported in mcg/mL
|
Serotype |
Normal value |
|
1 (1) |
≥1.0 |
|
2 (2) |
≥1.0 |
|
3 (3) |
≥1.0 |
|
4 (4) |
≥1.0 |
|
5 (5) |
≥1.0 |
|
8 (8) |
≥1.0 |
|
9N (9) |
≥1.0 |
|
12F (12) |
≥1.0 |
|
14 (14) |
≥1.0 |
|
17F (17) |
≥1.0 |
|
19F (19) |
≥1.0 |
|
20 (20) |
≥1.0 |
|
22F (22) |
≥1.0 |
|
23F (23) |
≥1.0 |
|
6B (26) |
≥1.0 |
|
10A (34) |
≥1.0 |
|
11A (43) |
≥1.0 |
|
7F (51) |
≥1.0 |
|
15B (54) |
≥1.0 |
|
18C (56) |
≥1.0 |
|
19A (57) |
≥1.0 |
|
9V (68) |
≥1.0 |
|
33F (70) |
≥1.0 |
Day(s) Performed
Monday through Friday
Report Available
4 to 6 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
86581
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| PN23M | S. pneumoniae IgG Ab,23 serotypes,S | 42366-5 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 620316 | Serotype 1 (1) | 85954-6 |
| 620317 | Serotype 2 (2) | 86039-5 |
| 620318 | Serotype 3 (3) | 86080-9 |
| 620319 | Serotype 4 (4) | 86107-0 |
| 620320 | Serotype 5 (5) | 86130-2 |
| 620321 | Serotype 8 (8) | 86147-6 |
| 620322 | Serotype 9N (9) | 86169-0 |
| 620323 | Serotype 12F (12) | 85977-7 |
| 620324 | Serotype 14 (14) | 85991-8 |
| 620325 | Serotype 17F (17) | 86009-8 |
| 620326 | Serotype 19F (19) | 86024-7 |
| 620327 | Serotype 20 (20) | 86045-2 |
| 620328 | Serotype 22F (22) | 86052-8 |
| 620329 | Serotype 23F (23) | 86064-3 |
| 620330 | Serotype 6B (26) | 27118-9 |
| 620331 | Serotype 10A (34) | 86098-1 |
| 620332 | Serotype 11A (43) | 86122-9 |
| 620333 | Serotype 7F (51) | 25296-5 |
| 620334 | Serotype 15B (54) | 40973-0 |
| 620335 | Serotype 18C (56) | 27395-3 |
| 620336 | Serotype 19A (57) | 40974-8 |
| 620337 | Serotype 9V (68) | 30153-1 |
| 620338 | Serotype 33F (70) | 40969-8 |
| 620404 | Interpretation | 69048-7 |
Forms
If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.