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Test Code TGMS Thyroglobulin Mass Spectrometry, Serum

Additional Codes

ALAB: YTGMS

PowerChart: 

MA Cerner: 

Useful For

Accurate measurement of serum thyroglobulin (Tg) in patients with known or suspected antithyroglobulin autoantibodies (TgAb) or heterophile antibodies (HAb)

 

Reflex testing of samples with previously unknown TgAb status that prove TgAb positive during immunoassay testing

 

Assisting in the differential diagnosis of early phase silent thyroiditis versus Graves disease in patients without thyroid cancer (the mass spectrometry-based method would only be required if these patients have TgAb or HAb)

Reporting Name

Thyroglobulin, Mass Spec., S

Specimen Type

Serum Red


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Red top

Acceptable: None (gel tubes/SST are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 1.25 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.75 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 7 days
  Frozen  416 days
  Ambient  72 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Reference Values

Healthy individuals with intact, functioning thyroid: ≤33 ng/mL

Day(s) Performed

Monday through Friday

Report Available

3 to 10 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

84432

LOINC Code Information

Test ID Test Order Name Order LOINC Value
TGMS Thyroglobulin, Mass Spec., S 3013-0

 

Result ID Test Result Name Result LOINC Value
62749 Thyroglobulin, Mass Spec., S 3013-0
35998 Interpretation 59462-2

Method Name

Tryptic Protein Fragmentation, purified with Immunocapture, Analysis by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

(This service is performed pursuant to an agreement with SISCAPA Assay Technologies Inc. covering US Patent 7,632,686)

Secondary ID

62749

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Oncology Test Request (T729)

-Renal Diagnostics Test Request (T830)