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HelpTest Code TTDGP Celiac Reflex Panel
Additional Codes
ALAB: TTDGP
Powerchart: Celiac Reflex Panel
MA Cerner: TT IgA and Gliadin IgA Reflex to IgG
Test Method
Multiplex Flow Immunoassay; BioRad BioPlex
Specimen Requirement
Serum is preferred, EDTA or heparinized plasma are also acceptable. Gel tubes are acceptable.
Additional Specimen Collection Information
Collect blood in a serum or plasma gel tube (EDTA or heparin).
- Minimum volume: 500 mcL
- Hemolysis: > 2+ not acceptable
- Lipemia: > 3+ must be ultracentrifuged
- Icterus: no significant interference noted
- Storage: specimen is stable for up to 7 days refrigerated;
freeze at -20oC for long term storage.
Thoroughly mix thawed specimens; it is also recommended to centrifuge thawed specimens to remove gross particulate matter. Avoid multiple freeze-thaw cycles (up to 3 cycles are acceptable).
Performance
Testing is performed Monday through Friday.
Routine: Typically completed within 24 hours after the specimen
arrives at the testing site.
STAT: Typically completed within 4 hours after the specimen arrives at the testing site.
CPT Code Information
83516 x 2
Useful For
Tissue Transglutaminase IgA
- Evaluating patients suspected of having celiac disease, including patients with compatible clinical symptoms, patients with atypical symptoms, and individuals at increased risk (family history,
- previous diagnosis with associated disorder, positivity for HLA DQ2 and/or DQ8)
- Screening test for dermatitis herpetiformis, in conjunction with endomysial antibody test
- Monitoring adherence to gluten-free diet in patients with dermatitis herpetiformis and celiac disease
Gliadin (Deamidated) IgA:
- Evaluating patients suspected of having celiac disease; this includes patients with symptoms compatible with celiac disease, patients with atypical symptoms, and individuals at increased risk of celiac disease
- Evaluating the response to treatment with a gluten-free diet
LOINC Code Information
46128-5 Tissue transglutaminase IgA Ab [Units/volume] in Serum
by Immunoassay
47393-4 Gliadin peptide IgA Ab [Presence] in Serum by
Immunoassay
Reference Value
Tissue Transglutaminase IgA:
- < 15.0 U/mL (Negative)
Tissue Transglutaminase (TTG) IgA Antibody test includes an assessment for IgA deficiency at no additional charge with reflex to Tissue Transglutaminas (TTG) IgG Antibody test. - ≥ 15.0 U/mL (Positive)
Gliadin (Deamidated) IgA:
- < 15.0 U/mL (Negative)
Gliadin (Deamidated) IgA Antibody test includes an assessment for IgA deficiency at no additional charge with reflex to Gliadin (Deamidated) IgG Antibody test. - ≥ 15.0 U/mL (Positive)