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Test Code SSA SS-A(Ro) Antibody

Important Note

Testing for SS-A/Ro antibodies is not useful in patients without demonstrable antinuclear antibodies.

Additional Codes

ALAB: SSA

Powerchart: Sjogren’s Antibodies (SSA)

MA Cerner: SS-A/Ro Antibodies, IgG

Test Method

Multiplex Flow Immunoassay; BioRad BioPlex

Specimen Requirement

0.5 mL of serum. Gel tubes are preferred.

Additional Specimen Collection Information

Collection Instructions:

  • Minimum volume: 500 mcL
  • Hemolysis: Samples with hemolysis >2+ are not acceptable
  • Lipemia: Samples with lipemia >3+ must be ultracentrifuged prior to analysis
  • Icterus: No interference
  • Storage: Stable for up to 7 days at 2-8°C.

Performance

Testing is performed Monday through Friday.

Reference Value

SS-A Antibody: Negative (<1 AI) Reported as an antibody index.

CPT Code Information

86235-SSA Antibody

Useful For

Evaluating patients with signs and symptoms of a connective tissue disease in whom the test for antinuclear antibodies is positive
A positive result for SS-A/Ro antibodies is consistent with connective tissue disease, including Sjogren syndrome, lupus erythematosus (LE), or rheumatoid arthritis.

 

A positive result for SS-A/Ro antibodies in a woman with LE prior to delivery indicates an increased risk of congenital heart block in the neonate.

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