Sign in →

Test Code ANASCR Antinuclear Antibody (ANA) Cascade

Additional Codes

ALab: ANASCR

Powerchart: ANA (Antinuclear Antibody) Profile

MA Cerner: ANA Antibody (ANA) Cascade

Specimen Requirement

0.5 mL of serum. Gel tubes are preferred.

Additional Specimen Collection Information

Collection Instructions:

  • Minimum volume: 500 mcL
  • Hemolysis: Samples with hemolysis >2+ are not acceptable
  • Lipemia: Samples with lipemia >3+ must be ultracentrifuged prior to analysis
  • Icterus: No interference
  • Storage: Stable for up to 7 days at 2-8°C.

Performance

Testing is performed Monday through Friday.

Reference Value

ANA Screen: Negative
A negative ANA result reflects antibodies absent or below the cut-off values for the following analytes: dsDNA, Chromatin, Ribosomal P, SS-A 60, SS-A 52, SS-B, Sm, SmRNP, RNP A, RNP 68, Scl-70, Jo-1, and Centromere B.

 

Antinuclear antibody will reflex to the individual antibodies listed when positive. Individual antibody tests may be ordered separately as appropriate. Possible reflex tests include:

        Double Stranded DNA

        Chromatin Antibody

        Ribosomal P Antibody

        SS-A (Ro) Antibody

        SS-B (La) Antibody

        Sm Antibody

        SmRNP Antibody

        RNP Antibody

        Centromere Antibody

        Scl-70 Antibody

        Jo-1 Antibody

CPT Code Information

86038-ANA Screen
86225-dsDNA Antibody
86235-Chromatin Antibody
83516-Ribosomal P Antibody
86235x5-SSA,SSB,Sm,SmRNP,RNP Antibodies
83516x3-Centromere B,SCL-70,Jo-1 Antibodies

Useful For

The ANA Screen detects the presence of clinically relevant circulating autoantibodies in serum and plasma. These autoantibodies may be useful as an aid in the diagnosis of systemic autoimmune diseases such as Systemic Lupus Erythematosus (SLE), Mixed Connective Tissue Disease (MCTD), Sjögren’s Syndrome (SS), Scleroderma (Systemic Sclerosis), Dermatomyositis, Rheumatoid Arthritis (RA), CREST Syndrome, and Raynaud’s Phenomenon.

Related Tests